Across TCGA patient cohorts, SLX4 protein abundance is significantly associated with the protein abundance of many other proteins, with 4,442 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SLX4-associated proteins across cancer lineages are RBBP6_T1066, FLI1_S79, and RILPL2. Each is linked with SLX4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLX4-to-partner and partner-to-SLX4 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SLX4→partner) and Y-score (partner→SLX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RBBP6_T1066 →	+0.709	+0.493	<.001	.001	3	2
LSCC	FLI1_S79 →	-0.540	-0.356	.001	<.001	3	2
LSCC	RILPL2 →	-0.361	-0.304	<.001	.004	3	2
LUAD	LIG1_S76 →	+0.862	+0.499	<.001	.001	3	2
LSCC	TECPR1_T414 →	-0.935	-0.348	.001	.001	3	2
LUAD	RBAK →	+0.647	+0.679	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,442 associations by consensus.

Exploration

SLX4 survival (RNA) · tumor vs normal (RNA) · all SLX4 data types