Across TCGA cell cohorts, SLX4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,104 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SLX4-associated GO terms across cancer lineages are Centrosome cycle, DNA double-strand break processing involved in repair via single-strand annealing, and Regulation of transcription of nucleolar large rRNA by RNA polymerase I. Each is linked with SLX4 in more than 18 cancer types. Because this analysis shows association rather than direction, both SLX4-to-partner and partner-to-SLX4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLX4→partner) and Y-score (partner→SLX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Centrosome cycle →	+0.084	+0.849	.001	.002	3	19
BONE	DNA double-strand break processing involved in repair via single-strand annealing →	+0.089	+0.993	<.001	<.001	3	18
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.218	+1.111	<.001	<.001	3	18
BONE	Double-strand break repair via single-strand annealing →	+0.089	+0.993	<.001	<.001	3	18
PANCREAS	Microtubule organizing center organization →	+0.085	+0.828	<.001	<.001	3	18
PANCREAS	DNA biosynthetic process →	+0.067	+0.549	.001	.002	2	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,104 associations by consensus.

Exploration

SLX4 survival (RNA) · tumor vs normal (RNA) · all SLX4 data types