SLX1B

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLX1B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,276 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLX1B-associated GO terms across cancer lineages are Epinephrine metabolic process, Negative regulation of telomere maintenance, and Oxidative demethylation. Each is linked with SLX1B in more than 8 cancer types. Because this analysis shows association rather than direction, both SLX1B-to-partner and partner-to-SLX1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epinephrine metabolic process grouped by SLX1B-low versus SLX1B-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLX1B→partner) and Y-score (partner→SLX1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UPPER_AERODIGESTIVE_TRACTEpinephrine metabolic process →+1.139+1.737<.001<.00139
URINARY_TRACTNegative regulation of telomere maintenance →+0.063+1.270.001.00137
OESOPHAGUSOxidative demethylation →-0.137-1.332.004.00528
BLOOD_LeukemiaResponse to dopamine →+0.103+0.816<.001<.00136
BLOOD_LeukemiaCellular response to dopamine →+0.103+0.816<.001<.00136
LUNG_NSCLC_LUADtRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation →-0.078-0.933<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,276 associations by consensus.

Epinephrine metabolic process by SLX1B expression — UPPER_AERODIGESTIVE_TRACT

Box plot of Epinephrine metabolic process in SLX1B-low vs SLX1B-high samples in UPPER_AERODIGESTIVE_TRACT.

Explore this box plot interactively →

Exploration