SLX1B

Across TCGA pan-cancer cohorts, SLX1B RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated SLX1B data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher SLX1B RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SLX1B expression acts as an unfavorable survival marker, although some lineages such as CHOL and BLCA show a favorable association.

KIRC, SARC, and CHOL are the cancer types where SLX1B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.521	0.680	<.001	48	view →
SARC	OS	Median	All	0.682	0.797	.008	28	view →
CHOL	DFS	Median	III,IV	0.647	0.127	.006	18	view →
KIRP	DFS	Median	III,IV	0.221	0.748	.017	16	view →
PRAD	DFS	Median	All	0.647	0.912	<.001	16	view →
UVM	DFS	Quartile	III,IV	0.250	0.740	.002	15	view →
KICH	OS	Tertile	II,III,IV	0.417	0.886	.006	13	view →
DLBC	DFS	Tertile	II,III,IV	0.306	1.000	.003	13	view →
UCEC	DFS	Tertile	All	0.857	0.919	.004	12	view →
COAD	DFS	Quartile	II,III,IV	0.663	0.773	.024	12	view →
BLCA	OS	Quartile	II,III,IV	0.585	0.306	.011	11	view →
SKCM	DFS	Quartile	II,III,IV	0.515	0.728	.010	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

SLX1B–KIRC (OS)

Open the KIRC breakdown →