SLU7

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, SLU7 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated SLU7 data layer compared with 22 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher SLU7 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLU7 expression acts as an unfavorable survival marker.

SKCM and UCEC are the cancer types where SLU7 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
SKCMDFSMedianIII,IV0.0290.613<.00112view →
UCECOSMedianIV0.2310.592.0366view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

SLU7–SKCM (DFS)

Kaplan–Meier survival curve for SLU7 mutant vs wild-type samples in SKCM.

Open the SKCM breakdown →

Exploration