SLU7

Across TCGA pan-cancer cohorts, SLU7 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of SLU7’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where SLU7 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SLU7 is over-expressed in tumor, although a few such as LUSC and THCA show the opposite, repressed pattern.

KIRC, LIHC, and LUSC are the cancer types where SLU7 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLU7 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	+0.513	<.001	11	view →
LIHC	Male	II,III,IV	+1.003	<.001	9	view →
LUSC	All	II,III,IV	−0.491	<.001	8	view →
THCA	Male	II,III,IV	−0.356	<.001	7	view →
CHOL	All	All	+1.775	<.001	5	view →
KICH	All	All	−0.755	<.001	5	view →
UCEC	All	All	−0.635	<.001	4	view →
KIRP	Male	II,III,IV	+0.324	.029	4	view →
BRCA	Female	All	−0.188	.001	4	view →
LUAD	All	II,III,IV	−0.208	.034	2	view →
HNSC	Female	III,IV	+0.345	.029	1	view →
ESCA	All	All	+0.308	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

SLU7–KIRC

Open the KIRC breakdown →