SLU7

Across TCGA patient cohorts, SLU7 mutation is significantly associated with the immune_cell of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLU7-associated genes across cancer lineages are Basophils, CD4+ Tem, and Eosinophils. Each is linked with SLU7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLU7-to-partner and partner-to-SLU7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Basophils grouped by SLU7-low versus SLU7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLU7→partner) and Y-score (partner→SLU7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Basophils →	+0.239	+2.584	.001	.011	3	2
STAD	CD4+ Tem →	+0.012	+3.450	.023	.036	3	1
SKCM	Eosinophils →	+0.075	+3.123	.006	.035	3	1
UCEC	Erythrocytes →	+0.028	+3.241	.008	.009	3	1
UCEC	lymphatic Endothelial cells →	-0.022	-3.419	.030	.005	3	1
UCEC	Myocytes →	+0.047	+3.246	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Basophils by SLU7 expression — UCEC

Explore this box plot interactively →