SLU7

Across TCGA cell cohorts, SLU7 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,947 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SLU7-associated GO terms across cancer lineages are Protein polyubiquitination, Alternative mRNA splicing, via spliceosome, and mRNA 3'-splice site recognition. Each is linked with SLU7 in more than 15 cancer types. Because this analysis shows association rather than direction, both SLU7-to-partner and partner-to-SLU7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein polyubiquitination grouped by SLU7-low versus SLU7-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLU7→partner) and Y-score (partner→SLU7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Protein polyubiquitination →	+0.058	+0.619	.001	.007	3	16
CNS	Alternative mRNA splicing, via spliceosome →	+0.106	+0.750	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	mRNA 3'-splice site recognition →	+0.115	+0.949	.006	<.001	2	14
BREAST	Regulation of transcription initiation by RNA polymerase II →	+0.064	+0.685	.001	.003	3	12
KIDNEY	Macroautophagy →	+0.065	+0.701	<.001	<.001	3	12
BLOOD_Lymphoma	Regulation of macroautophagy →	+0.052	+1.049	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,947 associations by consensus.

Protein polyubiquitination by SLU7 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →