SLU7

Across TCGA cell cohorts, SLU7 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible SLU7-associated genes across cancer lineages are SERPINA7, CST11, and GPR101. Each is linked with SLU7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLU7-to-partner and partner-to-SLU7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SERPINA7 grouped by SLU7-low versus SLU7-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLU7→partner) and Y-score (partner→SLU7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	SERPINA7 →	+0.006	+5.228	.005	.005	3	1
LUNG_NSCLC_LUAD	CST11 →	+0.151	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	GPR101 →	+0.012	+4.887	.004	.009	3	1
LUNG_NSCLC_LUAD	OR4D5 →	+0.019	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	OR6T1 →	+0.048	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	TARM1 →	+0.032	+5.662	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

SERPINA7 by SLU7 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →