SLMAP

Across TCGA cell cohorts, SLMAP mutation is significantly associated with the mutation status of many other genes, with 4,573 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLMAP-associated genes across cancer lineages are GRIA3, PTCHD1, and DDX39B. Each is linked with SLMAP in more than 4 cancer types. Because this analysis shows association rather than direction, both SLMAP-to-partner and partner-to-SLMAP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GRIA3 grouped by SLMAP-low versus SLMAP-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLMAP→partner) and Y-score (partner→SLMAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	GRIA3 →	+4.584	+4.584	.007	.007	1	5
BLOOD_Lymphoma	PTCHD1 →	+4.584	+4.584	.007	.007	1	4
BLOOD_Lymphoma	DDX39B →	+4.584	+4.584	.007	.007	1	4
BLOOD_Leukemia	LRRK1 →	+2.787	+3.962	<.001	<.001	1	4
BLOOD_Leukemia	MYH1 →	+2.728	+3.375	.003	.003	1	4
BLOOD_Lymphoma	THOC2 →	+5.584	+5.014	.003	.003	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,573 associations by consensus.

GRIA3 by SLMAP expression — BLOOD_Lymphoma

Explore this box plot interactively →