SLK

Across TCGA patient cohorts, SLK RNA expression is significantly associated with the protein abundance of many other proteins, with 16,000 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SLK-associated proteins across cancer lineages are HSPA13, TACC2, and CTNND1. Each is linked with SLK in more than 5 cancer types. Because this analysis shows association rather than direction, both SLK-to-partner and partner-to-SLK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLK versus HSPA13 in LUAD, with a Pearson correlation of -0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SLK→partner) and Y-score (partner→SLK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	HSPA13 →	-0.435	-0.441	<.001	<.001	3	6
LUAD	TACC2 →	+0.435	+0.330	<.001	.001	3	5
HNSC	CTNND1 →	+0.253	+0.698	<.001	<.001	3	5
HNSC	DNMBP →	+0.315	+0.571	<.001	<.001	3	5
COAD	INPP5F →	+0.497	+0.881	.007	<.001	2	6
BRCA	NAT10 →	-0.311	-0.425	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,000 associations by consensus.

SLK vs HSPA13 — LUAD

Explore this scatter interactively →