SLK

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLK protein abundance is significantly associated with the RNA expression of many other genes, with 17,837 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SLK-associated genes across cancer lineages are STN1, EIF3A, and ATAD1. Each is linked with SLK in more than 8 cancer types. Because this analysis shows association rather than direction, both SLK-to-partner and partner-to-SLK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLK versus STN1 in UCEC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLK→partner) and Y-score (partner→SLK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECSTN1 →+0.821+0.305<.001<.00139
COADEIF3A →+0.389+0.246<.001.00237
OVATAD1 →+0.598+0.270.005.00828
OVSFR1 →+0.732+0.433<.001<.00137
COADABRAXAS2 →+0.310+0.201<.001<.00137
BRCACCDC186 →+0.592+0.244<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 17,837 associations by consensus.

SLK vs STN1 — UCEC

Per-sample scatter of SLK vs STN1 in UCEC (Pearson r = 0.40).

Explore this scatter interactively →

Exploration