SLK

Across TCGA cell cohorts, SLK RNA expression is significantly associated with the go_rna of many other GO terms, with 3,898 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SLK-associated GO terms across cancer lineages are Phosphatidylinositol metabolic process, Phosphatidylinositol biosynthetic process, and Post-Golgi vesicle-mediated transport. Each is linked with SLK in more than 13 cancer types. Because this analysis shows association rather than direction, both SLK-to-partner and partner-to-SLK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phosphatidylinositol metabolic process grouped by SLK-low versus SLK-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLK→partner) and Y-score (partner→SLK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Phosphatidylinositol metabolic process →	+0.062	+1.031	<.001	<.001	3	14
OESOPHAGUS	Phosphatidylinositol biosynthetic process →	+0.061	+0.919	<.001	.002	3	12
SKIN	Post-Golgi vesicle-mediated transport →	+0.054	+0.867	.003	.007	2	13
UPPER_AERODIGESTIVE_TRACT	Viral translational termination-reinitiation →	+0.117	+1.172	<.001	<.001	3	12
BREAST	Protein localization to chromosome, telomeric region →	+0.085	+0.671	.003	.004	1	12
OVARY	Regulation of sister chromatid cohesion →	+0.116	+0.923	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,898 associations by consensus.

Phosphatidylinositol metabolic process by SLK expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →