SLITRK4

Across TCGA cell cohorts, SLITRK4 mutation is significantly associated with the RNA expression of many other genes, with 130 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLITRK4-associated genes across cancer lineages are CLEC20A, KNG1, and OR6C70. Each is linked with SLITRK4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLITRK4-to-partner and partner-to-SLITRK4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLEC20A grouped by SLITRK4-low versus SLITRK4-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLITRK4→partner) and Y-score (partner→SLITRK4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	CLEC20A →	+0.029	+4.196	<.001	.002	3	2
CNS	KNG1 →	+0.018	+4.315	<.001	.006	3	2
CNS	OR6C70 →	+0.275	+4.832	<.001	.002	3	2
CNS	SCGB1C1 →	+0.230	+5.566	<.001	<.001	3	2
LARGE_INTESTINE	F11 →	+0.026	+2.397	.007	.003	3	2
PANCREAS	OR2T35 →	+0.020	+5.614	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 130 associations by consensus.

CLEC20A by SLITRK4 expression — SKIN

Explore this box plot interactively →