SLITRK3

Across TCGA patient cohorts, SLITRK3 mutation is significantly associated with the RNA expression of many other genes, with 7,233 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLITRK3-associated genes across cancer lineages are BAP1, DVL2, and KIF15. Each is linked with SLITRK3 in more than 4 cancer types. Because this analysis shows association rather than direction, both SLITRK3-to-partner and partner-to-SLITRK3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BAP1 grouped by SLITRK3-low versus SLITRK3-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLITRK3→partner) and Y-score (partner→SLITRK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	BAP1 →	+0.259	+1.268	.001	<.001	3	5
UCEC	DVL2 →	+0.333	+1.262	<.001	<.001	3	5
LUAD	KIF15 →	+0.751	+2.096	<.001	<.001	3	5
UCEC	ZC3H14 →	+0.271	+1.272	<.001	<.001	3	5
LUAD	ZC3HC1 →	+0.260	+1.824	.001	.002	3	4
LUAD	GEMIN2 →	+0.560	+2.853	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,233 associations by consensus.

BAP1 by SLITRK3 expression — SKCM

Explore this box plot interactively →