SLITRK1

Across TCGA cell cohorts, SLITRK1 mutation is significantly associated with the RNA expression of many other genes, with 139 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLITRK1-associated genes across cancer lineages are ZP2, TAAR8, and DUSP21. Each is linked with SLITRK1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLITRK1-to-partner and partner-to-SLITRK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZP2 grouped by SLITRK1-low versus SLITRK1-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLITRK1→partner) and Y-score (partner→SLITRK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	ZP2 →	+0.015	+4.584	.005	<.001	3	2
OVARY	TAAR8 →	+0.196	+3.754	.005	.002	3	2
LUNG_SCLC	DUSP21 →	+0.031	+5.029	<.001	.006	3	2
BLOOD_Leukemia	ZIC5 →	+0.800	+3.474	<.001	.007	3	2
BLOOD_Leukemia	CT45A6 →	+0.089	+3.507	<.001	.004	3	2
SKIN	ALPI →	+0.007	+3.084	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 139 associations by consensus.

ZP2 by SLITRK1 expression — OVARY

Explore this box plot interactively →