SLIT2-IT1

Across TCGA patient cohorts, SLIT2-IT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,233 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SLIT2-IT1-associated proteins across cancer lineages are SLIT2, KANK2, and PRKG1. Each is linked with SLIT2-IT1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SLIT2-IT1-to-partner and partner-to-SLIT2-IT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLIT2-IT1 versus SLIT2 in UCEC, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SLIT2-IT1→partner) and Y-score (partner→SLIT2-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SLIT2 →	+0.672	+1.295	<.001	<.001	3	6
CCRCC	KANK2 →	+0.447	+0.681	<.001	<.001	3	5
CCRCC	PRKG1 →	+0.589	+0.847	<.001	<.001	3	5
CCRCC	FBLN1 →	+0.658	+1.086	<.001	<.001	3	5
UCEC	EPB41L2 →	+0.448	+1.196	<.001	<.001	3	5
CCRCC	C1orf198 →	+0.568	+0.763	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,233 associations by consensus.

SLIT2-IT1 vs SLIT2 — UCEC

Explore this scatter interactively →