SLFNL1-AS1

Across TCGA pan-cancer cohorts, SLFNL1-AS1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated SLFNL1-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher SLFNL1-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SLFNL1-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and HNSC show a favorable association.

ACC, BLCA, and LGG are the cancer types where SLFNL1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Median	All	0.673	0.903	<.001	101	view →
BLCA	OS	Median	III,IV	0.125	0.486	.001	58	view →
LGG	DFS	Median	All	0.636	0.836	<.001	54	view →
MESO	OS	Median	All	0.212	0.686	<.001	47	view →
UCS	DFS	Median	IV	0.952	0.367	.001	36	view →
HNSC	OS	Median	All	0.819	0.714	.005	35	view →
CESC	DFS	Median	II,III,IV	0.280	0.776	.002	34	view →
COAD	DFS	Median	All	0.705	0.846	.002	30	view →
UCEC	OS	Tertile	IV	0.583	0.219	.015	18	view →
PRAD	DFS	Quartile	All	0.822	0.929	.006	18	view →
KIRC	DFS	Median	All	0.562	0.708	.011	12	view →
LUSC	DFS	Quartile	III,IV	0.215	0.951	<.001	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

SLFNL1-AS1–ACC (OS)

Open the ACC breakdown →