SLFNL1-AS1

Across TCGA pan-cancer cohorts, SLFNL1-AS1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of SLFNL1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where SLFNL1-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SLFNL1-AS1 is over-expressed in tumor, although a few such as THCA and BLCA show the opposite, repressed pattern.

KIRC, HNSC, and STAD are the cancer types where SLFNL1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLFNL1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.228	<.001	9	view →
HNSC	All	All	+0.148	<.001	9	view →
STAD	Male	II,III,IV	+0.295	<.001	5	view →
READ	All	All	+0.311	.002	4	view →
COAD	Female	II,III,IV	+0.306	<.001	4	view →
CHOL	Female	All	+1.183	.022	2	view →
LUSC	All	All	+0.271	.015	2	view →
KIRP	All	IV	+0.270	.013	2	view →
BLCA	Female	All	+0.243	.043	2	view →
THCA	Female	All	−0.107	.019	2	view →
BLCA	Male	IV	−0.377	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 10 lineages.

SLFNL1-AS1–KIRC

Open the KIRC breakdown →