SLFN5

Across TCGA patient cohorts, SLFN5 protein abundance is significantly associated with the RNA expression of many other genes, with 12,422 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SLFN5-associated genes across cancer lineages are OAS2, XAF1, and CD6. Each is linked with SLFN5 in more than 7 cancer types. Because this analysis shows association rather than direction, both SLFN5-to-partner and partner-to-SLFN5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLFN5 versus OAS2 in COAD, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLFN5→partner) and Y-score (partner→SLFN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	OAS2 →	+1.410	+0.366	<.001	.001	3	8
HNSC	XAF1 →	+1.144	+0.481	<.001	<.001	3	7
BRCA	CD6 →	+0.948	+0.434	<.001	<.001	3	7
COAD	IFI44 →	+1.333	+0.349	<.001	.001	3	7
BRCA	GPR174 →	+1.012	+0.424	<.001	<.001	3	7
BRCA	CD226 →	+0.657	+0.693	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,422 associations by consensus.

SLFN5 vs OAS2 — COAD

Explore this scatter interactively →