SLF2

Across TCGA patient cohorts, SLF2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,662 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLF2-associated genes across cancer lineages are ABI3, STK32C, and CLEC4E. Each is linked with SLF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLF2-to-partner and partner-to-SLF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLF2 versus ABI3 in UCEC, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLF2→partner) and Y-score (partner→SLF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ABI3 →	+1.354	+0.597	<.001	<.001	3	2
UCEC	STK32C →	+1.454	+0.554	<.001	<.001	3	2
UCEC	CLEC4E →	+2.378	+0.501	<.001	<.001	3	2
UCEC	IFI35 →	+1.507	+0.477	.002	.001	3	2
BRCA	MTMR8 →	+0.549	+0.558	.001	.003	3	2
BRCA	SLC39A6 →	-1.869	-0.539	.004	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,662 associations by consensus.

SLF2 vs ABI3 — UCEC

Explore this scatter interactively →