SLF2

Across TCGA cell cohorts, SLF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,629 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLF2-associated GO terms across cancer lineages are Chromatin looping, Protein localization to site of double-strand break, and Positive regulation of maintenance of sister chromatid cohesion. Each is linked with SLF2 in more than 18 cancer types. Because this analysis shows association rather than direction, both SLF2-to-partner and partner-to-SLF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chromatin looping grouped by SLF2-low versus SLF2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLF2→partner) and Y-score (partner→SLF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Chromatin looping →	+0.120	+1.151	<.001	<.001	3	19
LIVER	Protein localization to site of double-strand break →	+0.109	+0.765	.002	<.001	2	19
SOFT_TISSUE	Positive regulation of maintenance of sister chromatid cohesion →	+0.142	+1.193	<.001	<.001	3	18
SOFT_TISSUE	Positive regulation of maintenance of mitotic sister chromatid cohesion →	+0.142	+1.193	<.001	<.001	3	18
SOFT_TISSUE	Regulation of sister chromatid cohesion →	+0.127	+1.286	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Centrosome cycle →	+0.088	+0.961	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,629 associations by consensus.

Chromatin looping by SLF2 expression — OVARY

Explore this box plot interactively →