SLF1

Across TCGA patient cohorts, SLF1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,283 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SLF1-associated genes across cancer lineages are CRYBB2P1, LGALS1, and HMGXB4. Each is linked with SLF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLF1-to-partner and partner-to-SLF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLF1 versus CRYBB2P1 in PDAC, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLF1→partner) and Y-score (partner→SLF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CRYBB2P1 →	+0.275	+0.514	<.001	.001	3	1
PDAC	LGALS1 →	+0.410	+0.506	.002	.001	3	1
PDAC	HMGXB4 →	+0.224	+0.490	.002	.002	3	1
PDAC	TOM1 →	+0.376	+0.659	.001	.002	3	1
PDAC	HMOX1 →	+0.587	+0.555	<.001	<.001	3	1
PDAC	PDGFB →	+0.498	+0.472	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,283 associations by consensus.

SLF1 vs CRYBB2P1 — PDAC

Explore this scatter interactively →