SLF1

Across TCGA cell cohorts, SLF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,468 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLF1-associated GO terms across cancer lineages are DNA strand elongation, Microtubule organizing center organization, and Mitotic nuclear division. Each is linked with SLF1 in more than 18 cancer types. Because this analysis shows association rather than direction, both SLF1-to-partner and partner-to-SLF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA strand elongation grouped by SLF1-low versus SLF1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLF1→partner) and Y-score (partner→SLF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	DNA strand elongation →	+0.216	+1.678	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Microtubule organizing center organization →	+0.100	+1.033	<.001	<.001	3	19
SOFT_TISSUE	Mitotic nuclear division →	+0.120	+1.325	<.001	<.001	3	18
SOFT_TISSUE	Positive regulation of maintenance of sister chromatid cohesion →	+0.145	+0.995	<.001	<.001	3	18
SOFT_TISSUE	Positive regulation of maintenance of mitotic sister chromatid cohesion →	+0.145	+0.995	<.001	<.001	3	18
SOFT_TISSUE	Kinetochore organization →	+0.168	+1.089	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,468 associations by consensus.

DNA strand elongation by SLF1 expression — OESOPHAGUS

Explore this box plot interactively →