SLCO5A1

Across TCGA patient cohorts, SLCO5A1 mutation is significantly associated with the total protein of many other genes, with 53 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLCO5A1-associated genes across cancer lineages are INPP4B, Cyclin-B1, and eEF2. Each is linked with SLCO5A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLCO5A1-to-partner and partner-to-SLCO5A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INPP4B grouped by SLCO5A1-low versus SLCO5A1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLCO5A1→partner) and Y-score (partner→SLCO5A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	INPP4B →	-0.509	-2.991	.008	.036	3	3
UCEC	Cyclin-B1 →	+0.567	+2.662	<.001	<.001	3	3
UCEC	eEF2 →	+0.233	+1.700	.022	.040	3	3
UCEC	ERK2 →	+0.172	+1.584	.001	.001	3	3
UCEC	ASNS →	+0.271	+1.514	.008	.014	3	3
STAD	Annexin_VII →	-0.228	-3.000	.003	.033	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 53 associations by consensus.

INPP4B by SLCO5A1 expression — COAD

Explore this box plot interactively →