SLCO4A1-AS1

Across TCGA pan-cancer cohorts, SLCO4A1-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated SLCO4A1-AS1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher SLCO4A1-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated SLCO4A1-AS1 expression acts as an unfavorable survival marker, although some lineages such as UVM and HNSC show a favorable association.

UVM, HNSC, and LUAD are the cancer types where SLCO4A1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	All	0.754	0.430	<.001	108	view →
HNSC	OS	Quartile	II,III,IV	0.832	0.671	<.001	106	view →
LUAD	DFS	Tertile	All	0.734	0.882	<.001	63	view →
UCS	DFS	Tertile	II,III,IV	0.144	0.529	.007	56	view →
LGG	DFS	Tertile	All	0.321	0.492	<.001	36	view →
LUSC	DFS	Median	All	0.570	0.707	.001	28	view →
COAD	OS	Tertile	All	0.831	0.924	.006	23	view →
THCA	OS	Median	IV	0.860	1.000	.016	20	view →
THYM	DFS	Quartile	All	0.774	1.000	.020	14	view →
READ	DFS	Median	II,III,IV	0.388	0.673	.014	12	view →
KIRP	OS	Tertile	III,IV	0.443	0.728	.024	11	view →
DLBC	DFS	Quartile	II,III,IV	0.355	1.000	.040	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

SLCO4A1-AS1–UVM (DFS)

Open the UVM breakdown →