SLCO4A1-AS1

Across TCGA pan-cancer cohorts, SLCO4A1-AS1 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of SLCO4A1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where SLCO4A1-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SLCO4A1-AS1 is over-expressed in tumor, although a few such as BRCA and BLCA show the opposite, repressed pattern.

COAD, STAD, and BRCA are the cancer types where SLCO4A1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLCO4A1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	III,IV	+2.824	<.001	12	view →
STAD	Male	All	+2.125	<.001	9	view →
BRCA	All	III,IV	−0.903	<.001	6	view →
LUAD	Female	All	+0.622	.002	4	view →
THCA	Male	All	+0.085	.010	4	view →
CHOL	All	All	+2.963	<.001	3	view →
READ	Female	All	+2.764	<.001	3	view →
BLCA	Female	III,IV	−0.601	.003	3	view →
HNSC	All	II,III,IV	−0.599	.022	3	view →
KICH	All	All	−0.392	.004	3	view →
PAAD	All	All	+1.739	.038	2	view →
ESCA	All	All	+1.651	.017	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

SLCO4A1-AS1–COAD

Open the COAD breakdown →