SLCO3A1

Across TCGA cell cohorts, SLCO3A1 mutation is significantly associated with the mutation status of many other genes, with 3,204 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLCO3A1-associated genes across cancer lineages are EP400P1, PCDHGA10, and TUT7. Each is linked with SLCO3A1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLCO3A1-to-partner and partner-to-SLCO3A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EP400P1 grouped by SLCO3A1-low versus SLCO3A1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLCO3A1→partner) and Y-score (partner→SLCO3A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	EP400P1 →	+4.870	+4.560	<.001	<.001	1	4
CNS	PCDHGA10 →	+5.044	+5.614	.003	.003	1	4
LARGE_INTESTINE	TUT7 →	+1.667	+1.916	.009	.009	1	4
BLOOD_Leukemia	ZNF831 →	+3.115	+4.080	.001	.001	1	4
BLOOD_Leukemia	CHD3 →	+2.870	+3.347	.009	.009	1	4
STOMACH	PLXNB1 →	+4.285	+3.357	.005	.005	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,204 associations by consensus.

EP400P1 by SLCO3A1 expression — BLOOD_Leukemia

Explore this box plot interactively →