Across TCGA patient cohorts, SLCO1B7 mutation is significantly associated with the RNA expression of many other genes, with 270 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SLCO1B7-associated genes across cancer lineages are RNA5SP489, RNU6-497P, and SERAC1. Each is linked with SLCO1B7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLCO1B7-to-partner and partner-to-SLCO1B7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLCO1B7→partner) and Y-score (partner→SLCO1B7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNA5SP489 →	+0.428	+7.640	<.001	.009	3	2
UCEC	RNU6-497P →	+0.484	+3.621	<.001	.004	3	2
SKCM	SERAC1 →	+0.620	+2.719	<.001	.003	3	2
SKCM	CARS2 →	+0.520	+3.334	<.001	.005	3	2
SKCM	LLPHP1 →	+0.068	+2.520	<.001	.008	3	2
SKCM	MIR4734 →	+0.237	+2.533	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 270 associations by consensus.

Exploration

SLCO1B7 survival (RNA) · tumor vs normal (RNA) · all SLCO1B7 data types