Across TCGA cell cohorts, SLCO1B7 mutation is significantly associated with the mutation status of many other genes, with 641 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLCO1B7-associated genes across cancer lineages are TMPPE, CHM, and CACNG3. Each is linked with SLCO1B7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLCO1B7-to-partner and partner-to-SLCO1B7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLCO1B7→partner) and Y-score (partner→SLCO1B7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TMPPE →	+5.672	+5.672	<.001	<.001	1	2
LARGE_INTESTINE	CHM →	+3.672	+4.799	.002	.002	1	2
LARGE_INTESTINE	CACNG3 →	+5.087	+4.523	.006	.006	1	2
LARGE_INTESTINE	ZNF2 →	+4.087	+5.044	.001	.001	1	2
LARGE_INTESTINE	IKZF5 →	+3.672	+4.799	.002	.002	1	2
LARGE_INTESTINE	APOL4 →	+4.672	+5.329	<.001	<.001	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 641 associations by consensus.

Exploration

SLCO1B7 survival (RNA) · tumor vs normal (RNA) · all SLCO1B7 data types