SLCO1B3

Across TCGA patient cohorts, SLCO1B3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,626 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible SLCO1B3-associated GO terms across cancer lineages are Sodium-independent organic anion transport, Pigment catabolic process, and Tetrapyrrole catabolic process. Each is linked with SLCO1B3 in more than 12 cancer types. Because this analysis shows association rather than direction, both SLCO1B3-to-partner and partner-to-SLCO1B3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sodium-independent organic anion transport grouped by SLCO1B3-low versus SLCO1B3-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLCO1B3→partner) and Y-score (partner→SLCO1B3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Sodium-independent organic anion transport →	-0.103	-0.850	<.001	.004	1	13
HNSC	Pigment catabolic process →	-0.070	-1.089	<.001	<.001	3	10
HNSC	Tetrapyrrole catabolic process →	-0.067	-1.168	<.001	<.001	3	8
ESCA	Ribonucleoside monophosphate catabolic process →	+0.051	+1.197	<.001	<.001	3	7
BLCA	ERBB2-EGFR signaling pathway →	+0.059	+0.908	<.001	<.001	3	7
STAD	Activation of cysteine-type endopeptidase activity →	+0.056	+0.722	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,626 associations by consensus.

Sodium-independent organic anion transport by SLCO1B3 expression — ESCA

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