SLCO1B3

Across TCGA patient cohorts, SLCO1B3 protein abundance is significantly associated with the RNA expression of many other genes, with 12,625 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SLCO1B3-associated genes across cancer lineages are SMARCA2, CD302, and N4BP2L1. Each is linked with SLCO1B3 in more than 8 cancer types. Because this analysis shows association rather than direction, both SLCO1B3-to-partner and partner-to-SLCO1B3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLCO1B3 versus SMARCA2 in LSCC, with a Pearson correlation of 0.86.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLCO1B3→partner) and Y-score (partner→SLCO1B3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SMARCA2 →	+1.137	+0.576	<.001	<.001	3	9
OV	CD302 →	+0.696	+0.375	<.001	<.001	3	7
HNSC	N4BP2L1 →	+0.717	+0.431	<.001	<.001	3	7
UCEC	RNU2-25P →	+1.312	+0.462	<.001	<.001	3	7
OV	AK3 →	+0.538	+0.336	.004	.003	3	6
LSCC	SNAPC3 →	+0.524	+0.456	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,625 associations by consensus.

SLCO1B3 vs SMARCA2 — LSCC

Explore this scatter interactively →