SLCO1B3

Across TCGA cell cohorts, SLCO1B3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,434 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible SLCO1B3-associated GO terms across cancer lineages are Blood coagulation, intrinsic pathway, Blood coagulation, extrinsic pathway, and Positive regulation of calcium ion transport into cytosol. Each is linked with SLCO1B3 in more than 7 cancer types. Because this analysis shows association rather than direction, both SLCO1B3-to-partner and partner-to-SLCO1B3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Blood coagulation, intrinsic pathway grouped by SLCO1B3-low versus SLCO1B3-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLCO1B3→partner) and Y-score (partner→SLCO1B3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Blood coagulation, intrinsic pathway →	+0.361	+2.414	<.001	<.001	3	8
OVARY	Blood coagulation, extrinsic pathway →	+1.147	+1.712	<.001	<.001	3	6
OESOPHAGUS	Positive regulation of calcium ion transport into cytosol →	+0.304	+3.433	<.001	<.001	3	6
BREAST	Regulation of plasma membrane repair →	+0.134	+0.800	.003	.007	3	6
OVARY	Regulation of positive chemotaxis →	+0.240	+1.908	<.001	<.001	3	6
LIVER	G protein-coupled opsin signaling pathway →	-0.137	-1.868	.002	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,434 associations by consensus.

Blood coagulation, intrinsic pathway by SLCO1B3 expression — OESOPHAGUS

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