SLCO1B1

Across TCGA patient cohorts, SLCO1B1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,064 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SLCO1B1-associated genes across cancer lineages are JPH1, LDLRAP1, and DACT3-AS1. Each is linked with SLCO1B1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLCO1B1-to-partner and partner-to-SLCO1B1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLCO1B1 versus JPH1 in CCRCC, with a Pearson correlation of -0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLCO1B1→partner) and Y-score (partner→SLCO1B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	JPH1 →	-0.961	-0.754	.001	.001	3	2
BRCA	LDLRAP1 →	-0.794	-0.477	<.001	.004	3	2
UCEC	DACT3-AS1 →	-1.133	-0.739	<.001	.005	3	2
LUAD	CHRDL1 →	+1.512	+0.983	.003	<.001	3	1
LUAD	VEGFA →	-0.916	-0.718	.001	.001	3	1
LUAD	ROPN1B →	+0.380	+0.634	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,064 associations by consensus.

SLCO1B1 vs JPH1 — CCRCC

Explore this scatter interactively →