SLCO1B1

Across TCGA cell cohorts, SLCO1B1 RNA expression is significantly associated with the RNA expression of many other genes, with 2,353 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLCO1B1-associated genes across cancer lineages are SLCO1B7, SLCO1B3, and CFAP54. Each is linked with SLCO1B1 in more than 11 cancer types. Because this analysis shows association rather than direction, both SLCO1B1-to-partner and partner-to-SLCO1B1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLCO1B1 versus SLCO1B7 in LARGE_INTESTINE, with a Pearson correlation of 0.90.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLCO1B1→partner) and Y-score (partner→SLCO1B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SLCO1B7 →	+1.369	+0.692	<.001	<.001	3	12
STOMACH	SLCO1B3 →	+3.453	+0.548	<.001	<.001	3	9
BLOOD_Leukemia	CFAP54 →	+0.292	+0.014	.001	.001	3	2
BREAST	SLCO1A2 →	+0.429	+0.111	<.001	<.001	3	2
UPPER_AERODIGESTIVE_TRACT	CLSTN3 →	+1.300	+0.300	<.001	.003	3	2
LARGE_INTESTINE	OSBPL10 →	+1.356	+0.706	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,353 associations by consensus.

SLCO1B1 vs SLCO1B7 — LARGE_INTESTINE

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