SLCO1A2

Across TCGA patient cohorts, SLCO1A2 mutation is significantly associated with the RNA expression of many other genes, with 3,588 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLCO1A2-associated genes across cancer lineages are RNU6-933P, ARHGAP19, and RNU6-572P. Each is linked with SLCO1A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLCO1A2-to-partner and partner-to-SLCO1A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-933P grouped by SLCO1A2-low versus SLCO1A2-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLCO1A2→partner) and Y-score (partner→SLCO1A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-933P →	+0.509	+3.178	<.001	.006	3	3
UCEC	ARHGAP19 →	+0.386	+1.541	.002	.002	3	3
KIRC	RNU6-572P →	+0.332	+5.377	<.001	.005	3	3
UCEC	LINC00294 →	+0.310	+2.021	.009	<.001	3	2
BLCA	KRTAP12-2 →	+0.033	+4.147	.002	.009	3	2
BLCA	S100A11P10 →	+0.105	+4.444	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,588 associations by consensus.

RNU6-933P by SLCO1A2 expression — LUAD

Explore this box plot interactively →