SLC9C2

Across TCGA patient cohorts, SLC9C2 mutation is significantly associated with the RNA expression of many other genes, with 5,928 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC9C2-associated genes across cancer lineages are SKA1, ENO1, and MCM6. Each is linked with SLC9C2 in more than 4 cancer types. Because this analysis shows association rather than direction, both SLC9C2-to-partner and partner-to-SLC9C2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SKA1 grouped by SLC9C2-low versus SLC9C2-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9C2→partner) and Y-score (partner→SLC9C2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	SKA1 →	+1.011	+3.459	<.001	.005	3	5
STAD	ENO1 →	+0.776	+3.195	<.001	.009	3	5
UCEC	MCM6 →	+0.488	+1.949	<.001	<.001	3	5
UCEC	GMNN →	+0.531	+1.684	<.001	<.001	3	5
UCEC	INCENP →	+0.483	+1.844	<.001	<.001	3	4
UCEC	CDC123 →	+0.256	+1.969	.005	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,928 associations by consensus.

SKA1 by SLC9C2 expression — STAD

Explore this box plot interactively →