SLC9C2

Across TCGA patient cohorts, SLC9C2 mutation is significantly associated with the total protein of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC9C2-associated genes across cancer lineages are Caspase-7-cleavedD198, GAPDH, and Cyclin-B1. Each is linked with SLC9C2 in more than 4 cancer types. Because this analysis shows association rather than direction, both SLC9C2-to-partner and partner-to-SLC9C2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by SLC9C2-low versus SLC9C2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9C2→partner) and Y-score (partner→SLC9C2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Caspase-7-cleavedD198 →	+0.935	+3.008	.022	.019	3	5
SKCM	GAPDH →	+0.430	+1.432	.005	.003	3	3
UCEC	Cyclin-B1 →	+0.513	+2.000	<.001	.002	3	3
COAD	C-Raf →	+0.221	+3.008	.003	.019	3	3
UCEC	PCNA →	+0.130	+1.247	.025	.038	3	3
UCEC	ATM →	-0.372	-1.834	.002	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

Caspase-7-cleavedD198 by SLC9C2 expression — COAD

Explore this box plot interactively →