SLC9C2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC9C2 RNA expression is significantly associated with the go_rna of many other GO terms, with 370 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC9C2-associated GO terms across cancer lineages are Establishment of protein localization to membrane, ATF6-mediated unfolded protein response, and Response to cocaine. Each is linked with SLC9C2 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC9C2-to-partner and partner-to-SLC9C2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to membrane grouped by SLC9C2-low versus SLC9C2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9C2→partner) and Y-score (partner→SLC9C2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UPPER_AERODIGESTIVE_TRACTEstablishment of protein localization to membrane →+0.057+0.015<.001.00833
BLOOD_LeukemiaATF6-mediated unfolded protein response →+0.052+0.268.007<.00133
BLOOD_LeukemiaResponse to cocaine →+0.092+0.371.001.00333
BLOOD_LeukemiaCellular response to lipoprotein particle stimulus →+0.106+0.342<.001<.00133
OVARYRegulation of skeletal muscle contraction by regulation of release of sequestered calcium ion →-0.190-0.087<.001.00533
OVARYModulation of process of another organism →+0.050+0.089.003.00624
Each partner links to its Q-omics profile. Showing the 6 strongest of 370 associations by consensus.

Establishment of protein localization to membrane by SLC9C2 expression — UPPER_AERODIGESTIVE_TRACT

Box plot of Establishment of protein localization to membrane in SLC9C2-low vs SLC9C2-high samples in UPPER_AERODIGESTIVE_TRACT.

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Exploration