SLC9C2

Across TCGA cell cohorts, SLC9C2 mutation is significantly associated with the RNA expression of many other genes, with 478 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC9C2-associated genes across cancer lineages are KRTAP12-3, SEH1L, and CHRNB3. Each is linked with SLC9C2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC9C2-to-partner and partner-to-SLC9C2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP12-3 grouped by SLC9C2-low versus SLC9C2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9C2→partner) and Y-score (partner→SLC9C2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	KRTAP12-3 →	+0.058	+4.539	<.001	.007	3	2
LARGE_INTESTINE	SEH1L →	+0.733	+3.212	.003	.006	3	2
PANCREAS	CHRNB3 →	+0.021	+4.011	<.001	.009	3	1
PANCREAS	DIPK1C →	+0.028	+4.491	<.001	.003	3	1
LUNG_SCLC	OR5H6 →	+0.025	+5.029	<.001	.006	3	1
LUNG_SCLC	OOSP4B →	+0.233	+5.643	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 478 associations by consensus.

KRTAP12-3 by SLC9C2 expression — BLOOD_Leukemia

Explore this box plot interactively →