SLC9B1

Across TCGA cell cohorts, SLC9B1 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC9B1-associated genes across cancer lineages are TEX47, PDILT, and OR2T4. Each is linked with SLC9B1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC9B1-to-partner and partner-to-SLC9B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TEX47 grouped by SLC9B1-low versus SLC9B1-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9B1→partner) and Y-score (partner→SLC9B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	TEX47 →	+0.160	+4.044	.002	.009	3	1
LUNG_SCLC	PDILT →	+0.102	+4.643	<.001	.004	3	1
LUNG_SCLC	OR2T4 →	+0.062	+4.643	<.001	.004	3	1
LARGE_INTESTINE	AVP →	+0.048	+3.217	<.001	.006	3	1
LARGE_INTESTINE	DNASE1L3 →	+0.075	+3.491	.005	.008	3	1
LUNG_NSCLC_LUAD	CCL19 →	+0.146	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

TEX47 by SLC9B1 expression — LUNG_SCLC

Explore this box plot interactively →