SLC9A7

Across TCGA patient cohorts, SLC9A7 mutation is significantly associated with the RNA expression of many other genes, with 3,303 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC9A7-associated genes across cancer lineages are PRC1, NUDC, and SNRPD3. Each is linked with SLC9A7 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC9A7-to-partner and partner-to-SLC9A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRC1 grouped by SLC9A7-low versus SLC9A7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9A7→partner) and Y-score (partner→SLC9A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PRC1 →	+0.748	+3.353	<.001	<.001	3	3
SKCM	NUDC →	+0.477	+3.373	<.001	.004	3	3
UCEC	SNRPD3 →	+0.259	+1.740	.005	.002	3	3
UCEC	TOMM22 →	+0.340	+2.120	.001	<.001	3	3
UCEC	ERI1 →	+0.488	+2.436	<.001	.001	3	3
UCEC	NCAPG →	+0.736	+2.110	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,303 associations by consensus.

PRC1 by SLC9A7 expression — UCEC

Explore this box plot interactively →