SLC9A7

Across TCGA pan-cancer cohorts, SLC9A7 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of SLC9A7’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where SLC9A7 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SLC9A7 is over-expressed in tumor.

HNSC, LUAD, and BLCA are the cancer types where SLC9A7 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLC9A7 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	+0.762	<.001	11	view →
LUAD	Male	All	+1.396	<.001	9	view →
BLCA	Male	III,IV	+2.144	<.001	8	view →
LUSC	Female	All	+1.677	<.001	8	view →
COAD	Male	All	+1.052	<.001	8	view →
LIHC	All	All	+0.391	<.001	7	view →
STAD	All	All	+0.524	.022	4	view →
CHOL	All	All	+2.292	<.001	3	view →
KIRP	All	II,III,IV	+0.747	.013	3	view →
READ	Male	All	+1.536	.027	2	view →
PRAD	All	All	+0.708	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

SLC9A7–HNSC

Open the HNSC breakdown →