SLC9A3R1

Across TCGA patient cohorts, SLC9A3R1 mutation is significantly associated with the RNA expression of many other genes, with 163 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC9A3R1-associated genes across cancer lineages are GOLGA2P3Y, RNU6-1195P, and MIR920. Each is linked with SLC9A3R1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC9A3R1-to-partner and partner-to-SLC9A3R1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GOLGA2P3Y grouped by SLC9A3R1-low versus SLC9A3R1-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9A3R1→partner) and Y-score (partner→SLC9A3R1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	GOLGA2P3Y →	+0.038	+5.655	<.001	.004	3	1
HNSC	RNU6-1195P →	+0.393	+6.111	<.001	.002	3	1
HNSC	MIR920 →	+0.475	+5.124	<.001	.008	3	1
HNSC	OR2A12 →	+0.044	+5.015	.002	.009	3	1
HNSC	RPL34P3 →	+0.166	+5.505	<.001	.004	3	1
HNSC	SAR1AP4 →	+0.096	+5.182	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 163 associations by consensus.

GOLGA2P3Y by SLC9A3R1 expression — HNSC

Explore this box plot interactively →