SLC9A3

Across TCGA patient cohorts, SLC9A3 mutation is significantly associated with the RNA expression of many other genes, with 1,897 significant associations in total. COAD shows the largest number of these associations.

The most reproducible SLC9A3-associated genes across cancer lineages are MIR6766, LINC02489, and TRMU. Each is linked with SLC9A3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC9A3-to-partner and partner-to-SLC9A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6766 grouped by SLC9A3-low versus SLC9A3-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9A3→partner) and Y-score (partner→SLC9A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR6766 →	+0.437	+5.575	<.001	.004	3	3
COAD	LINC02489 →	+1.516	+2.700	<.001	.006	3	3
UCEC	TRMU →	+0.414	+3.839	<.001	<.001	3	3
UCEC	PSMC3IP →	+0.453	+2.828	.004	.001	3	3
UCEC	NARS1 →	+0.357	+2.238	.009	.006	3	3
COAD	SENP3-EIF4A1 →	+0.182	+2.767	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,897 associations by consensus.

MIR6766 by SLC9A3 expression — BRCA

Explore this box plot interactively →