SLC9A1

Across TCGA cell cohorts, SLC9A1 mutation is significantly associated with the RNA expression of many other genes, with 490 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC9A1-associated genes across cancer lineages are USP17L18, SEPTIN3, and BAG2. Each is linked with SLC9A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC9A1-to-partner and partner-to-SLC9A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, USP17L18 grouped by SLC9A1-low versus SLC9A1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC9A1→partner) and Y-score (partner→SLC9A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	USP17L18 →	+0.006	+4.887	<.001	.009	3	2
LARGE_INTESTINE	SEPTIN3 →	+1.060	+3.451	.007	.002	3	2
LARGE_INTESTINE	BAG2 →	+1.037	+3.364	.002	.002	3	2
LARGE_INTESTINE	HELLS →	+0.928	+3.067	<.001	.009	3	2
LARGE_INTESTINE	PIMREG →	+0.862	+3.169	.003	.006	3	2
LARGE_INTESTINE	ARL3 →	+0.546	+3.364	.008	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 490 associations by consensus.

USP17L18 by SLC9A1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →