SLC8B1

Across TCGA pan-cancer cohorts, SLC8B1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SLC8B1 data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SLC8B1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated SLC8B1 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

LUAD, CCRCC, and GBM are the cancer types where SLC8B1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.382	0.825	.026	10	view →
CCRCC	OS	Median	II,III,IV	0.106	1.000	.010	8	view →
GBM	OS	Median	All	0.321	0.695	.010	6	view →
LSCC	OS	Median	All	1.000	0.919	.019	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SLC8B1–LUAD (OS)

Open the LUAD breakdown →