SLC8B1

Across TCGA cell cohorts, SLC8B1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,676 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SLC8B1-associated GO terms across cancer lineages are Regulation of cardiac muscle cell membrane potential, Protein localization to plasma membrane, and Calcium export from the mitochondrion. Each is linked with SLC8B1 in more than 17 cancer types. Because this analysis shows association rather than direction, both SLC8B1-to-partner and partner-to-SLC8B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cardiac muscle cell membrane potential grouped by SLC8B1-low versus SLC8B1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC8B1→partner) and Y-score (partner→SLC8B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of cardiac muscle cell membrane potential →	+0.258	+1.353	.001	.002	3	18
BONE	Protein localization to plasma membrane →	+0.123	+1.170	<.001	<.001	3	15
LARGE_INTESTINE	Calcium export from the mitochondrion →	+0.180	+1.175	<.001	<.001	3	14
BONE	Viral process →	+0.123	+1.372	<.001	<.001	3	14
SOFT_TISSUE	Positive regulation of protein localization to plasma membrane →	+0.105	+1.442	<.001	<.001	3	14
BONE	Membrane raft organization →	+0.158	+0.883	<.001	.003	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,676 associations by consensus.

Regulation of cardiac muscle cell membrane potential by SLC8B1 expression — OESOPHAGUS

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