SLC8B1

Across TCGA cell cohorts, SLC8B1 mutation is significantly associated with the RNA expression of many other genes, with 65 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC8B1-associated genes across cancer lineages are CLPS, SLC30A3, and HAUS8. Each is linked with SLC8B1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC8B1-to-partner and partner-to-SLC8B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLPS grouped by SLC8B1-low versus SLC8B1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC8B1→partner) and Y-score (partner→SLC8B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	CLPS →	+0.087	+5.662	.008	.002	3	1
LARGE_INTESTINE	SLC30A3 →	+0.799	+3.212	.009	.006	3	1
LARGE_INTESTINE	HAUS8 →	+0.557	+3.212	.002	.006	3	1
LARGE_INTESTINE	GRSF1 →	+0.480	+3.212	.006	.006	3	1
LARGE_INTESTINE	TTPA →	+1.030	+3.212	<.001	.006	3	1
LARGE_INTESTINE	VAX1 →	+0.540	+3.005	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 65 associations by consensus.

CLPS by SLC8B1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →