SLC8A2

Across TCGA cell cohorts, SLC8A2 mutation is significantly associated with the RNA expression of many other genes, with 248 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC8A2-associated genes across cancer lineages are CBLIF, IL9, and OOSP4B. Each is linked with SLC8A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC8A2-to-partner and partner-to-SLC8A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CBLIF grouped by SLC8A2-low versus SLC8A2-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC8A2→partner) and Y-score (partner→SLC8A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	CBLIF →	+0.072	+4.199	<.001	.007	3	1
BREAST	IL9 →	+0.040	+4.781	<.001	.003	3	1
BREAST	OOSP4B →	+0.030	+4.781	<.001	.003	3	1
SKIN	SPDYC →	+0.347	+2.518	.006	.006	3	1
BLOOD_Leukemia	OR1Q1 →	+0.210	+3.714	.008	.005	3	1
BLOOD_Leukemia	TAS2R1 →	+0.031	+3.289	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 248 associations by consensus.

CBLIF by SLC8A2 expression — BREAST

Explore this box plot interactively →